Born in Rome, De Girolamo began his career in Florence as an actor in the theatre during the 1980s and he participated in events such as Festival dei Due Mondi.
He later went on to become a voice dubber and worked as a regular dubbing artist for Alan Cumming, Vincent Gallo, Matthew Modine and Ulrich Tukur.
Other actors De Girolamo occasionally dubbed included Adam Sandler, Clive Owen, Johnny Depp, Tim Roth, Kenneth Branagh, Colin Firth and Guy Pearce.
In De Girolamo's animated roles, he gave his voice to Master Crane in the Italian dubs of the first two Kung Fu Panda movies, Delbert Doppler in Treasure Planet, Bear, Treelo and various other characters in Bear in the Big Blue House, Fungus in Monsters, Inc., Gurgle in Finding Nemo and he also voiced Guido in various foreign dubbed versions of Cars.
[2] From 2004 until his death in 2012, De Girolamo served as the President of the ANAD, which is a dubbing company based in Italy.