[6] The show takes place in "Sunny Patch" (a tiny town made of common forest items), populated by anthropomorphic bugs, and primarily focuses on the Spider family.

The episodes follow the children's adventures playing in Sunny Patch and learning life lessons, such as being kind to others, being imaginative, having responsibility, and being curious about the world around them.

Qubo aired repeats of the show from 1 October 2018 until it discontinued on 28 February 2021 due to Scripps' acquisition.

[citation needed] A video game based on the series, titled Miss Spider's Sunny Patch Friends: Harvest Time Hop and Fly was developed by Shin'en Multimedia and published by The Game Factory for the Nintendo DS in 2006.

[12][13] The game's plot involves Miss Spider, her husband Holley, and their gang of buggies harvesting food and preparing for the coming of winter.