Danville High School is a comprehensive public secondary school located in Danville, Arkansas, United States, for students in grades nine through twelve.

[3] The assumed course of study for students is to complete the Smart Core curriculum developed by the Arkansas Department of Education (ADE), which requires students complete at least 22 units for graduation.

Course offerings include regular and Advanced Placement classes and exams with opportunities for college credit via AP exam or via concurrent credit at University of Arkansas Community College at Morrilton (UACCM) and Arkansas Tech University (ATU).

Competition is primarily sanctioned by the Arkansas Activities Association with student-athletes competing in football, basketball (boys/girls), competitive cheer, dance, golf (boys/girls), baseball, softball, tennis (boys/girls), and track and field (boys/girls).

[6] The school mascot "Little Johns" is a rough English translation of the French words Petit Jean, words synonymous with the local legend of a heroic young French girl which also gives the name to a nearby river, mountain and Arkansas' first state park.