It was serialized in Akita Shoten's Bessatsu Shōnen Champion magazine from December 2012 to October 2023.

An anime television series adaptation produced by Nexus aired from January to March 2020.

17-year-old high school sophomore Kaname Sudō accepts an online invitation by a friend to play an app game called Darwin's Game, unbeknownst to him that it involves a fight between life and death.

It is revealed later in the series that the Game Master is one of many in the multiverse and is actually benevolent, albeit in the greater good way.

[8] The series is directed by Yoshinobu Tokumoto and written by Shū Miyama, the writer of the FLIPFLOPs duo and also original creator of the manga series, with animation by studio Nexus and character designs by Kazuya Nakanishi.