He is known for co-creating and directing the animated series Pocoyó, Jelly Jamm, Pirata et Capitano, and Mola Noguru, among other business initiatives.

David Cantolla has been a founding partner and non-executive president of the eSports club Movistar Riders, which compete in some of the video games such as Fortnite, League Of Legends or Call Of Duty, among others.

Together with Colman López, Luis Gallego, and Guillermo García Carsi, he created the animation series Pocoyó, named following a linguistic play by his daughter Vega.

[9] In 2014, alongside Ana Gervás, he co-founded Colección SOLO,[10] which features works by approximately 270 artists from 20 countries.

The collection collaborates with museums and galleries, including exhibitions such human product by filip custic[11] at Parco Museum[12][13] (Tokio), The Garden of Earthly Delights through the works of Colección SOLO at Matadero Madrid,[14][15][16] NGV MuseumTriennial [17][18][19] l (Australia), or with Mario Klingemann works at AI: More than Human at Barbican Centre (London),[20] among others.