David D. Mitchell (July 31, 1806 – May 23, 1861) was an American fur trader and regional superintendent of Indian Affairs at St.

[3] Mitchell enlisted in the United States Army at the start of the Mexican–American War, during which he rose to Lieutenant Colonel in recognition of his service during the Doniphan's Expedition.

[5] The Bureau of Indian Affairs sought to "civilize" Native Americans, which they believed fur traders were in the best position to assist with policy and enforcement.

"[6] Mitchell sought to actuate safe passage for westward pioneers as negotiated in the Treaty of Fort Laramie (1851), while he also wanted to ensure that Native Americans received a fair settlement for the travelers crossing through their traditional hunting lands, which greatly reducing the population of buffalo and other game.

[7] He said, Humanity calls loudly for some interposition on the part of the American government to save, if possible, some portion of these ill-fated tribes; and this, it is thought, can only be done by furnishing them with the means, and gradually turning their attention to agricultural pursuits.

Mary filed for divorce in 1845, citing her husband's drinking habit, severe temper, and abusive language.