in physiology at Oxford University in the laboratory of Denis Noble for work on the sodium pump in cardiac muscle.

Eisner's early research focused on the regulation of intracellular sodium in cardiac muscle and the effects on contraction.

[13] He has identified the factors that regulate the calcium content of the sarcoplasmic reticulum[14][15] and how this is altered in disease.

Eisner is married to Susan Wray, professor of cellular and molecular physiology at the University of Liverpool, with whom he has three children.

[6] Eisner was elected as a Fellow of The Academy of Medical Sciences in 1999[23] and The International Society for Heart Research in 2001.