David Mayo (born August 18, 1993) is an American professional football linebacker.

He played college football for the Texas State Bobcats and was selected by the Carolina Panthers in the fifth round of the 2015 NFL draft.

[5][6] Mayo was part of the Panthers team that played in the Super Bowl 50 loss to the Denver Broncos.

[10] In Week 5 against the New England Patriots, Mayo recorded a team high 13 tackles and a sack.

[19] After missing the Week 15 game against the Philadelphia Eagles, he was placed back on the active roster on December 23.