[1] In June 2005 Vicenza acquired Biondini outright after winning the bid mediated by Lega Calcio for €202,500.

[5]) After a single season, signed a loan deal with the newly promoted Serie A club Atalanta on 24 August 2012 for €200,000.

[5][7][8][9] On 23 January 2014, Biondini left for Sassuolo in a temporary deal for €200,000,[10] with an option to purchase,[11] re-joining Genoa teammate Antonio Floro Flores (loan) and Thomas Manfredini (definitive).

He wore the prestigious number 10 shirt, but just made one appearance as a substitute in the last match of the group stage.

Biondini made his senior national team debut on 14 November 2009 during a friendly match against the Netherlands.