She writes and lectures extensively about superstition,[3] cryptozoology, religion and belief in the paranormal,[4] with special regard to the folklore, psychology and sociology behind these phenomena, and has been introduced as a "vampire expert".

[6] Hyde has contributed to several motion pictures as a staff member and coordinator in the makeup department, responsible for prosthetics and creature effects, including for the horror films Doghouse and 1408.

[1] Hyde's current website, deborahhyde.com, features blogposts and videos in which she takes an investigative approach to the interconnectedness of folklore, belief systems, and fear from unknown, natural phenomena.

[13] In her public appearances and writings, the following supernatural phenomena have been covered extensively: Hyde has been invited to speak at several different events including Skeptics in the Pub gatherings all across the UK (Winchester,[17] Liverpool,[24] Birmingham,[22] Wycombe,[25] Manchester,[23] Greenwich,[26] etc.)

Hyde has spoken twice at the "Skeptics on the Fringe" in Edinburgh with two of her lectures, "Interview With a Vampire Expert" and "The Natural History of the European Werewolf", both of which were received well with the sceptical audience.

[36] As editor-in-chief, Hyde has been working with an international advisory board of experts from many different fields, some of whom are globally recognised scientists, science educators and science enthusiasts, including Susan Blackmore, Stephen Fry, Derren Brown, Brian Cox, Richard Dawkins, Edzard Ernst, Robin Ince, PZ Myers, Phil Plait, Massimo Polidoro, Simon Singh, James Randi and Richard Wiseman.

The prize is officially awarded by The Skeptic magazine in several categories, agreed upon by a committee featuring sceptics including Chris French, Richard Wiseman, Wendy Grossman, Jon Ronson and Simon Singh.

[39] In a 2018 interview with Susan Gerbic, Hyde revealed that she is writing a book to be called Unnatural Predators that explores common themes in human folklore throughout history using a combination of historical, psychological, and anthropological perspectives.