Debre Birhan University (DBU) is a public university in the city Debre Birhan, Amhara Region, Ethiopia.

It is one of thirteen new universities which were established in 2007 by the Ethiopian government.

[2] The foundation of the university was laid down in May 2005 and the building of the first phase was started in May 2006.

Instruction began in January 2007 with the enrolment of 725 students in the Faculty of Education with two streams, namely Businesses Education and Natural Science teaching.

In the academic year of 2007/8, three additional Faculties (Business and Economics, Health Science and Agriculture) were opened, and the enrolment reached 2483.