Deep Run is an unincorporated community and census-designated place (CDP) in southern Lenoir County, North Carolina, United States.

Today, Deep Run is still an agricultural area, with several businesses and light industries.

The community provides a fire service, water and sewer, banking, and a postal route.

The main thoroughfare through the area is the North Carolina Highway 11 Bypass.

The town is a quiet town with no stoplights, three churches, Pleasant Hill Masonic Lodge #304, a few small businesses, and South Lenoir High School.