Deep Run is a tributary of Tohickon Creek which is located in Bedminster Township, Bucks County, Pennsylvania, in the United States.

The removal of trees at one time and erosion has lessened its depth.

The Deep Run schoolhouse dates to 1746 when land was deeded to the Mennonites for this purpose, the structure was a log building.

[2][3] Deep Run rises just over a half mile south of Dublin west of Pennsylvania Route 313 (Dublin Pike) and is northeast oriented for a short distance where it turns northwest for about a mile, then turns again northeast until it meets with Tohickon Creek near Randts Mill, about a mile from Pipersville.

Deep Run lies in a band of the Brunswick Formation in the Newark basin formed during the Jurassic and Triassic.