Del Rio is an unincorporated, urban community in Hillsborough County, Florida, United States.

The community is known as "The Fishbowl" to locals because many streets in the area are named for fish.

[citation needed] Del Rio is included within the East Lake-Orient Park census-designated place.

Tampa bounds Del Rio to the west, the Hillsborough River to the north, U.S. Route 92 to the south, and 56th Street (SR 583) to the east.

The 40th Street Bridge on County Road 585A travels over the Hillsborough River in Del Rio.