It plies route from Pacita Complex, San Pedro, Laguna to Novaliches, Quezon City.

It also offers provincial routes operated under its sister companies, Dela Rosa Express and N. Dela Rosa Liner, plying routes from Metro Manila to Batangas City, Batangas, and Lucena City, Quezon, respectively.

[2] Following the accident, the Land Transportation Franchising Regulatory Board (LTFRB) ordered the preventive suspension of Dela Rosa Transit and ordered all of the company's drivers to undergo drug testing and road safety seminars within 15 days of the announcement.

[3][4] Despite his claims that the brakes on the bus failed, he has been charged with reckless imprudence resulting in multiple injuries and damage to property.

[6] Dela Rosa Transit maintains and utilizes UD Nissan Diesel, Golden Dragon, Guilin Daewoo, Hino, Hyundai Aero Queen, Hyundai Universe Space Luxury, and King Long units, with roughly a total number of 300 buses, including those from N. Dela Rosa Liner.