Demetrios Chomatenos or Chomatianos (Greek: Δημήτριος Χωματηνός/Χωματιανός, 13th century), Eastern Orthodox Archbishop of Ohrid from 1216 to 1236, was a Byzantine priest and judge.
His comprehensive legal education allowed him to exert substantial influence as judge, arbiter, confessor and advisor to the Byzantine imperial house.
According to the eminent Byzantinist Donald Nicol, Chomatenos' court at Ohrid was a rare centre of stability and law in an uncertain and tumultuous era; "From Kerkyra in the west to Drama in the east, from Dyrrachion in the north to Ioannina and Arta in the south, plaintiffs and defendants brought their problems to the humane and learned Archbishop".
He also played an important role in the rivalry of the two main post-Fourth Crusade Byzantine Greek successor states, the Empire of Nicaea and Epirus.
That changed in 1219, when Patriarch Manuel I of Constantinople (at that time residing in Nicaea), created a new Archbishopric for Serbia by appointing Sava Nemanjić as the first Serbian Archbishop.