Nichols was coached by Mike Hart at St. Andrew's High School, where he helped his club to a 28–8 record and won the New England Prep School Athletic Conference title, tallying 15 points and 13 rebounds in the championship game against Lawrence Academy.

[6] In his sophomore year, Nichols would start the first eight games of the season before he was forced out of the lineup with a back injury.

[8] Nichols' senior season proved to be his best one at Syracuse, as he was a unanimous selection for the All-Big East First Team.

He also set a Syracuse record in Big East games with a career-high[8] 37 points, including seven three-pointers, to go along with 10 rebounds against St.

[10] In March 2007, Nichols was elected to participate in the 19th Annual State Farm College Three-Point Championship.

Originally, the Knicks had wanted Nichols to play in Italy because they had 17 contracts and only 15 roster spots.

[14] Then on October 29, he was signed by the Cleveland Cavaliers to fill the 15th spot on their opening day roster.

[15] On December 5, 2007, Nichols was waived to clear roster space after the Cavs re-signed Anderson Varejão to end a contract dispute.

[23] In November 2010, he signed a contract with French club JA Vichy, until the end of the season.

[35] On August 5, 2018, Nichols signed a deal with the Italian club Sidigas Avellino for the 2018–19 LBA season.

[36] Nichols was a member of the 2002 USA Development Festival East Team that finished 3-2 and earned the silver medal.

[37] Nichols was invited to try out for the 2004 USA Basketball World Championship For Young Men's Qualifying Team.