Dendrophryniscus skuki is a species of toad in the family Bufonidae.

It is endemic to northeastern Brazil and only known from its type locality in the municipality of Itacaré, state of Bahia.

[1] The holotype is an adult male with a stout build and measuring 26 mm (1.0 in) in snout–vent length.

The venter and ventral surfaces of arms and thighs are cream with diffuse gray stains and dots.

[1] The holotype was collected from a near-coastal locality at 13 m (43 ft) above sea level.