It was initially located in an old factory building in Charlottenburg which had been only slightly modernized.
Under Aronson's leadership, the institute developed one of the first successful commercially produced antitoxic antisera against diphtheria, in direct competition with Emil von Behring, which was claimed by Schering to be much more effective than Behring's serum.
[6] The Department of Bacteriology remained in Charlottenburg due to the stables and laboratories being located there.
During the Cold War the department moved to Schering's headquarters in Wedding (Müllerstraße 170–172).
Georg Henneberg, the institute's former director, became President of the Federal Health Agency in 1969.