[2] The title is a blend of the Spanish words desamor (heartbreak) and metamorfosis (metamorphosis), with an emphasis on amor (love).

[6] The third single released was "Tick Tock" in which she sings with Farina and Sofía Reyes that peaked #9 on Billboard's Latin Pop Digital Songs Sales.

[7] On May 4, 2021, the singer announced the release of the album for the next day 14, in her Instagram page, suggesting that fans to reserve the album on their favorite digital platforms in order to be the first to listen it and have exclusive access to the "Universo desAMORfosis" website where they would find exclusive content and surprises.

[8] She also posted the album cover which she appear showing her body adorned with jewels and pearls in golden tones, in the center there is a dagger and a heart, while on her head has a very resplendent crown.

[10][11][12] A week later on May 18, 2021, Thalía appeared as a special guest on The Today Show to talk about the album and promote it some more.