Deshler is a village in Henry County, Ohio, United States.

[8] Since the early 1900s the Baltimore and Ohio Railroad provided a large economic presence.

Deshler, once called "The Crossroads of the B&O," was where the B&O's Detroit/Toledo to Cincinnati line crossed the very busy Chicago to Washington, D.C., mainline.

[12] CSX Transportation owns two lines (formerly Baltimore and Ohio and Chessie System), which run through the community, hosting approximately 50 to 70 trains daily and are popular among train enthusiasts.

[13] A YouTube channel called Virtual Railfan operates a continuous live webcast from the "diamond" intersection; trains may also be observed from "Crossroads Park".

25.1% of all households were made up of individuals, and 11.8% had someone living alone who was 65 years of age or older.

24.8% of all households were made up of individuals, and 13.1% had someone living alone who was 65 years of age or older.

Public education for the village is administered by the Patrick Henry Local School District.