Grona triflora, known as creeping tick trefoil or three-flower beggarweed, is a plant in the family Fabaceae.

[1][2][3] Grona triflora (Desmodium triflorum) contains alkaloids including N,N-dimethyltryptophan methyl ester, dimethyltryptamine-N-oxide, hypaphorine (structurally related to plakohypaphorine), phenylethylamine, hordenine, tyramine, and trigonelline.

[4][5] Creeping tick trefoil has been utilized in folk medicine.

Conditions it has been used for include wounds, diarrhea, rheumatism, dysentery, and skin diseases.

[6] Known substances found in trefoils include alkaloids and flavonoids.