He played college football for the University of California, Berkeley, and was selected by the Green Bay Packers in the sixth round of the 2007 NFL draft and later won Super Bowl XLV with the team over the Pittsburgh Steelers.

He was named the Northern California Conference Defensive Most Valuable Player and was a First-team JC Gridwire All-American.

Bishop immediately won a starting job upon his arrival at Cal and picked up second-team All-Pac-10 honors.

He started all 12 games at middle linebacker and led the team with 89 tackles, one forced fumble, and two pass deflections.

In 2006, Bishop started all 13 games and was a Third-team All-American choice by Rivals.com, earning honorable mention from The NFL Draft Report, and being placed on the Butkus Award watchlist.

During his second season Bishop made his first career start in a week 14 game against the Houston Texans, recording 12 tackles and a sack.

He started the remaining 12 games and finished the season with 103 tackles, 3 sacks, 2 forced fumble and 1 interception, which was returned for a touchdown.

[5] He was a starter and also recovered a crucial fumble in Super Bowl XLV, after Clay Matthews knocked the ball loose from Rashard Mendenhall, which was a key play in the Packers' 31–25 win over the Pittsburgh Steelers.

[7] On August 9, 2012, in a preseason game against the San Diego Chargers, Bishop sustained a significant injury to his hamstring which required surgical repair.

On August 27, 2012, the Green Bay Packers placed Bishop on injured reserve after the hamstring injury he sustained in the preseason game against the San Diego Chargers.