The Detroit Line is a freight railroad line owned and operated by the Norfolk Southern Railway in the U.S. states of Michigan and Ohio.

The line begins south of Gibraltar Road in Gibraltar, Michigan as a continuation of the Conrail Detroit Line, and runs southwest to Toledo, Ohio, consisting of two separate and parallel tracks.

The Toledo, Canada Southern and Detroit Railway opened a parallel line, just to the east, in 1873.

With the 1930 lease of the Michigan Central Railroad by the New York Central Railroad, both lines were placed under NYC operation.

[2][3] The lines passed to Conrail, and were assigned to Norfolk Southern in Conrail's 1999 breakup; they are now used through a directional running setup, in which southbound trains use the old DM&T and northbound trains use the old TCS&D.