Playing for the school's basketball team, she was a part of three state champions and averaged 26 points per game in her senior year.

[1][2] Though DeShields graduated with her bachelor's degree after her second season at Tennessee, she retained a year of eligibility for college basketball.

[3] DeShields signed with Çukurova Basketbol of the Turkish Super League, where she averaged 17.4 points, 6.4 rebounds, and 3.8 assists per game.

On September 11, 2019, she played in her first career postseason game and scored 25 points, as the Chicago Sky defeated the Phoenix Mercury 105–76.

An MRI following the injury revealed that she had a tumor (a lumbar spinal schwannoma) in her spine, which posed a serious risk of permanent paralysis.

After surgery to remove the tumor, DeShields suffered tremors and involuntary spasms and spent months rehabilitating without certainty about whether she would be able to return to play.

[12] The Sky entered the playoffs as the sixth seed, and made their way to the 2021 WNBA Finals, winning the series in four games against the Phoenix Mercury.

[14] On February 5, 2024, DeShields signed a one-year deal to return to the Chicago Sky, three seasons after her original departure.