Two of her best-known roles were Susan Rogers in The Indian Fighter (co-starring Kirk Douglas) and Peg in Planes, Trains and Automobiles.

In 2003, she appeared in It Runs in the Family with her ex-husband Kirk, her son Michael and her grandson Cameron.

Douglas' father was from a prominent Bermudian family, present on the island since the early 17th century.

Her ancestry included English, Irish, Welsh, Dutch, Scottish, Belgian, and French.

In It Runs in the Family, Douglas appeared with her former husband, Kirk Douglas, son Michael and grandson Cameron, and later appeared on an episode of CBS's Cold Case and in the Season 15 ER episode "Heal Thyself" (2008), the year that she retired from acting.

During the war, Douglas was serving in the U.S. Navy when he saw the May 3, 1943, issue of Life magazine, with a photograph of Dill on the cover.