DicF RNA is a non-coding RNA that is an antisense inhibitor of cell division gene ftsZ.

[1] DicF is bound by the Hfq protein which enhances its interaction with its targets.

Pathogenic E. coli strains possess multiple copies of sRNA DicF in their genomes, while non-pathogenic strains do not.

DicF and Hfq are both necessary to reduce FtsZ protein levels, leading to cell filamentation under anaerobic conditions.

[2] This molecular or cell biology article is a stub.