She originally came from the Macedonian highlands and her family were petty landholders in Europus.
Her brother Seleucus I Nicator was one of the Diadochi of Alexander the Great and her paternal uncle was a Greek soldier called Ptolemy.
She had married an unnamed Greek nobleman and had two sons: Diodotus and Nicomedes.
Diodotus, as a nephew of Seleucus I, would become Seleucid satrap of Bactria and his son, Diodotus I Soter would rebel in 255 BC, forming the rival Diodotid Kingdom (see Seleucid Dynastic Wars).
Her mother’s alleged sexual relations with Apollo to the allegation that the oracle of the Branchidae that greeted her brother as ‘King’ in 312 BC (see Didyma).