Diego Aguirre (born 23 September 1974 in Montevideo) is a former Uruguayan rugby player.
He played for Carrasco Polo Club, in Uruguay, and for US Tours, in France, in 2004/2005.
Aguirre is one of the best players from his country, having his debut for Uruguay, on 7 March 1995, in a 9–28 loss to Canada.
Aguirre has scored 11 tries, 17 conversions and 26 penalties, in an aggregate of 154 points.
He was the top scorer for his country, in 1999, with one conversion and four penalties, 19 points in aggregate.