Diegodendron is a monotypic genus of flowering plants belonging to the family Bixaceae.

The only known species is Diegodendron humbertii.

[2] Its native range is Madagascar.

[2] The genus and species were circumscribed by René Paul Raymond Capuron in Adansonia, n.s., vol.3 on page 385-386 in 1963.

[2] The genus name of Diegodendron is in honour of Diego Suárez also known as Diego Soares de Melo, Diego Suarez de Melo and the "Galego", who was a 16th-century Portuguese navigator and explorer (plus dendron Greek for tree).