Dienestrol (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name) (brand names Dienoestrol, Denestrolin, Dienol and many others[a]), also known as dienoestrol (BANTooltip British Approved Name), is a synthetic nonsteroidal estrogen medication of the stilbestrol group which is or was used to treat menopausal symptoms in the United States and Europe.

[1][2][3][4] It has been studied for use by rectal administration in the treatment of prostate cancer in men as well.

[5] The medication was introduced in the U.S. in 1947 by Schering as Synestrol and in France in 1948 as Cycladiene.

[7] Dienestrol diacetate (brand names Faragynol, Gynocyrol, others) also exists and has been used medically.

This drug article relating to the genito-urinary system is a stub.