Dillon High School is a public high school in Dillon, South Carolina, United States.

It is located on 1730 Highway 301 North, approximately 5 miles (8 km) from the border of North Carolina and South Carolina.

The current schoolhouse was built in 1970, with additions in 2000.

The school itself dates back to the late 1800s, with portions of 1896 and 1910 buildings still in use for other educational purposes.

Timothy Gibbs serves the school as principal, and D. Ray Rogers is the superintendent of the school's district.