Flowers was an early enrollee at Oklahoma and was injured in the spring game but was healthy for his freshman season.

[9] On October 10, 2018, Flowers was signed to the Jacksonville Jaguars practice squad, but was released the next day.

Flowers was picked in the tenth round of the 2020 XFL Draft by the Dallas Renegades.

[15] Dimitri is the son of Erik Flowers, a former NFL defensive end who was a first round pick of the Buffalo Bills in 2000.

[16] His brother, Braeden Flowers, is a current defensive end for the SMU Mustangs.