[1] As a senior, Flowers was a first-team All-Big 12 Conference selection and led the team with 79 tackles, two interceptions, and eight pass breakups.
[4] The Seahawks previously acquired the pick used to select Flowers as part of a trade that sent Marshawn Lynch to the Oakland Raiders.
[10] Head coach Pete Carroll named Flowers a starting cornerback after injuries to both Maxwell and Johnson.
Flowers primarily covered Pro Bowl wide receiver Emmanuel Sanders during the game and allowed 10 receptions on 11 targets for 135 yards and a 43-yard touchdown.
[17] Flowers served in a specialty role covering tight ends, most notably holding Travis Kelce to just 25 yards in Week 17 against the Kansas City Chiefs.
[18] Flowers began the 2022 season as the third cornerback on the depth chart, behind Chidobe Awuzie and Eli Apple, though he continued his role as the team's tight end coverage specialist.
In Week 15 against the Tampa Bay Buccaneers, Flowers recorded his only interception with the Bengals, helping the team begin their comeback to score 31-unanswered points in the second half to win the game 34–23.