Dimitrie Ghica or Ghika (Albanian: Gjika) (31 May 1816 – 15 February 1897) was a Romanian politician.

A prominent member of the Conservative Party, he served as Prime Minister between 1868 and 1870.

He married Charlotte Duport, and they had two daughters, Maria and Iza.

Ghica was a member of the Macedo-Romanian Cultural Society.

[1] He died in Bucharest at the age of 80 and was buried in the city's Bellu Cemetery; his tomb was designed by architect Ion Mincu.