Diodia virginiana is a plant species in the Rubiaceae, common name Virginia buttonweed.

It is a spreading, matted perennial with opposite leaves, often mottled because of a virus that attacks the foliage.

The species can become a nuisance weed, hard to eradicate because of underground parts that remain behind when you try to pull up the plant.

[1] Diodia virginiana is native to Cuba, Nicaragua, Mexico, Connecticut, and the south-central and southeastern United States.

[2] The species is also naturalized in Japan, Taiwan and northern California.