Diplopterys cabrerana is a shrub native to the Amazon Basin, spanning the countries of Brazil, Colombia, Ecuador and Peru.

[1] In the Quechua languages it is called chaliponga or chagropanga; in parts of Ecuador it is known as chacruna—a name otherwise reserved for Psychotria viridis.

D. cabrerana additionally produces 5-MeO-DMT, a less common structural analog.

[1] Leaf samples were found to be 0.17-1.75% N,N-DMT,[1] but only trace amounts of N-methyltetrahydro-beta-carboline occur in the leaves.

The cuttings are either planted in soil directly, or rooted first in water.