She made her television debut on Manapporuttam serial alongside Prem Prakash.
While Padmini was studying at NSS College, Changanacherry, she was selected by her teachers to play the central character in a telefilm titled Anakha, which was to be produced by the college's newly formed theatre club.
She acted as a village girl from a pulluvan background in the film.
[4] Padmini was spotted by director P. Vasu and got her Tamil film debut in the 2011 film Puli Vesham, for which she was asked to change her name to Divya Padmini, adding her mother's maiden name to her name.
She made her Tamil debut in Sun TV's serial Pillai Nila and she also acted in Kayitham, in which she plays a school teacher called Parvathy, produced by Samuthirakani.