The infrastructure of the university (general area of constructions and buildings is 126049 square meters estimated at 29,8 mln.

The foundation ceremony of Ekaterinoslav's Higher Mining Technical School (EHMTS) was conducted on October 12, 1899, and in April of the next year construction of the institution's new educational buildings began.

From the date of its founding the university was equipped with a two department library, a mineralogical museum, chemical, mechanical and probe laboratories, and offices for each discipline.

On June 19, 1912 the State Legislative body adopted a resolution on restructuring the EHMTS into a fully equipped Mining Institute.

In the 20s and 30s the process of forming scientific schools was continued, and therefore during the late 1930s the Mining Institute lost a significant part of its staff (about 30 persons, among which there were a number of outstanding professors), however, the institution withstood these losses and kept preparing highly professional specialists for industry and science.

As a result of the Second World War in 1941–1945 about 300 teachers, staff members and students left for the front within the first few days of hostilities commencing.

However, after the German invasion of the USSR and later Lower Dnieper Offensive, many of the institute's buildings were in ruin and required extensive reconstruction before the staff was able to move its educational activities back into them.

After the war, on November 21, 1949 the Mining Institute was awarded with the Order of the Red Banner and a number of its staff members received high state awards (26 orders and 17 medals) for scientific achievements and success in training engineering and technical staff for the national economy.

By 1951/52 academic year all the buildings of the institute had been completely rebuilt, with a new experimental study range for boring, a geological museum, and new laboratories and dormitories being put into use.

In February 2002 the institution was finally restructured and became the "National Mining University"; around the same time it started to widen its academic offering.

Today it is one of the leading higher educational institution of the country in geological prospecting and mining fields.

Much of the university is located on a central site in the city of Dnipro, close to the municipal historical museum and scientific library.

These museums are entirely run by the institution's staff and students and are funded from its budget; the collections are expanded with the help of donors and items which are taken on loan.

The two museums are both currently located in the main building (1st Corpus) of NMU on Dmytro Yavornytsky Prospekt.

The polytechnic owns a number of hostels for the use of its students who wish to live on or near the grounds and facilities of the university.

However demand for places in the university's hostels is often very high, making it impossible to house all the students who wish to live in them.