Dobrodeia Mstislavna of Kiev (Cyrillic: Добродея Мстиславна; baptized Eupraxia [Εὐπραξία] or Irene [Εἰρήνη]; died 16 November 1131) was a Byzantine empress by marriage to co-emperor Alexios Komnenos.

[4] In the imperial court of Constantinople, she became a part of a circle of women intellectuals, notably Alexios' aunt Anna Comnena, and the noblewoman Irene, known as a patron of astrologers and scholars.

[2] She was encouraged to find her own scholarly interest, studied extensively and was described by contemporaries: "She was not born in Athens, but she learned all the wisdom of the Greeks".

[2] The writer Theodore Balsamon noted that she "displayed a fascination with healing methods" and that she formulated medical salves and described their efficiency in a treatise on entitled "Ointments" (Greek "Alimma"), which is regarded as the first treatise on medicine written by a woman.

[4] Following her death, Alexios Komnenos is believed to have married his next spouse Kata of Georgia.