Domenico Bollani (1514–1579) was a diplomat and politician of the Republic of Venice, and as Bishop of Brescia from 1559 to 1579 he was a leading figure of the Catholic reform.

In 1556 he was appointed lieutenant (governor) of Friuli where he successfully managed a crisis due to famine and plague: an arch in Udine (the Arco Bollani built in 1556 and attributed to Andrea Palladio) remembers his activity.

[3] Even if he was not an ecclesiastic, he was proposed as the new bishop of Brescia by the citizen of the town, and this candidature was approved by both the Republic of Venice and by Pope Paul IV who formally appointed him on 14 March 1559.

Following the requests of the council, he founded the seminary in 1568, he gathered a diocesan synod in 1574 and was anxious to personally visit the parishes of the diocese of Brescia.

When in 1577 the plague spread in the city, in a moment's hesitation he left the town, then he chose to return to take care of the sick, following the example of Charles Borromeo.