(died 1587) was a Roman Catholic prelate who served as Bishop of Asti (1569–1587).

[1] Domenico della Rovere was born into a noble family from Asti, he belonged to the Dominican Order.

He was ordained a priest in the Order of Preachers.

[2] On 3 Mar 1569, he was appointed during the papacy of Pope Pius V as Bishop of Asti.

This article about a 16th-century Italian Catholic bishop or archbishop is a stub.