It was serialized in Kodansha's Weekly Shōnen Magazine from April 2014 to June 2020, with its chapters collected in 28 tankōbon volumes.

As the door swings open, Natsuo is taken aback to discover that Tsukiko Tachibana, the woman his father plans to marry, has two daughters: his longtime crush, Hina, and her younger sister, Rui.

The story delves into the controversial and complex issues of romantic relationships that involve student-teacher dynamics and step-sibling bonds, while also highlighting the themes of youth, family, friendships, learning, growing up, career, happiness and trust.

Written and illustrated by Kei Sasuga, Domestic Girlfriend was serialized in Kodansha's Weekly Shōnen Magazine from April 23, 2014,[6] to June 10, 2020.

[1] The series is directed by Shōta Ihata and written by Tatsuya Takahashi, with animation by studio Diomedéa.

[20] MVM Entertainment have acquired the distribution rights via Sentai Filmworks for the United Kingdom and Ireland.

Nik Freeman felt that the manga's stepsibling love triangle was a contrivance and that the sexual elements were a waste of Sasuga's talents, but complimented the drama and comedy, along with the characterization.