Domeykodactylus is an extinct genus of dsungaripterid pterosaur from the Early Cretaceous (Berriasian-Albian)-age Santa Ana Formation at Quebrada de la Carreta in Antofagasta, Chile.

The genus was named in 2000 by David Martill, Eberhard Frey, Guillermo Chong Diaz and Charles Michael Bell.

The specific name honors geologist Cecilia Demargasso of the Universidad Católica del Norte, "who was so kind to us".

The bone structure of the crest consists of vertical trabeculae, narrow struts; it was this texture that had originally been mistaken for the fine filter teeth of Pterodaustro.

The describers found Domeykodactylus similar to both the Ctenochasmatidae and Dsungaripteridae in the crest; because of the elevated tooth sockets it was assigned to the latter group.