The land holding covered an area that ran from Redondo Beach into the west, to Compton in the east and the harbor in the south.

The rancho spread across a territory that comprises neighborhoods that are now Compton, Gardena, Carson, Redondo Beach, Torrance, Palos Verdes Estates, Lomita, Rolling Hills Estates, Rancho Palos Verdes, San Pedro, Wilmington, Harbor City, and part of Long Beach.

The Dominguez basketball team also has a strong tradition, having produced NBA players such as Cedric Ceballos, Tyson Chandler, Brandon Jennings, Dennis Johnson and Tayshaun Prince.

The Dominguez High School Red & Gold Soul Marching Band have performed at the Nickelodeon Kid's Choice Awards, Home Depot Battle of the Bands, Nike ads, Boost Mobile basketball tournaments, Major League Baseball Urban Youth Academy games and L.A. Sparks Season Openers.

In 2000, educators Catherine Borek, Karen Greene and an all-student cast produced the first theatrical production to take place at Dominguez in over two decades.