[1] She married the consul Decimus Haterius Agrippa, who died in 32 as a victim of Tiberius' reign of terror.

In 33 Domitia married the witty, wealthy, and influential Gaius Sallustius Crispus Passienus.

Thereby, Crispus became the stepfather of Agrippina's son Lucius Domitius Ahenobarbus (Nero), who was Domitia's nephew.

Nero was visiting her at the time, and she commented that when he shaved his beard (a Roman symbolic act, usually performed during a ceremony at the age of twenty-one), she would gladly die peacefully.

According to a rumor, he then ordered the doctors to administer a fatal dose of laxative to his aunt and seized her property while she was dying.