[2][3] Lucilla through her mother had inherited a great fortune, which included a tile and brick factory near Rome, close to the river Tiber.

Lucilla married Marcus Annius Verus, a praetor, who came from a wealthy senatorial family.

With Verus, she had two children, a son, the future Roman Emperor Marcus Aurelius (26 April 121) and a daughter Annia Cornificia Faustina (122/123 – between 152 and 158).

In Lucilla's household, the future Roman Emperor Didius Julianus was educated and through her support he was able to start his legal career.

In his Meditations, Marcus Aurelius describes her as a 'pious and generous' person who lived a simple life (1.3n).