Dompoase Senior High School (also known as DOSS) is a mixed second cycle institution in Dompoase in the Adansi North District in the Ashanti Region of Ghana.

[4] In 2014, the headmaster of the school was Mr. Opoku Asamoah.

[5][6] In 2016, the headmistress of the school was Ms. Doris Bimpong.

[4] Eric Kwaku Kusi was a former physics teacher at the school and in 2018, Mr. Haruna Oppong was the headmaster of the school.

[7] Anglogold Ashanti provided books to the school, Akrofuom SHS, Asare Bediako SHS and others.