It operates under the Council for the Indian School Certificate Examinations and takes students from the lower kindergarten through grade twelve.

[1] The school was established in 1937, and is run by the Salesians of Don Bosco (SDB) a minority institution within the Catholic Church.

Don Bosco Self-employment was started in August 1978 for the young men of the locality who are school drop-outs to enable them to learn a trade and earn their livelihood.

Joseph, the Salesian Provincial in the presence of Mariano Uguet, who had been instrumental in acquiring and setting up the institution, and Attilio Colussi, the first rector.

A computer centre was set up in December 1986, and the following year the school celebrated its Golden Jubilee, with a function presided over by the governor of West Bengal Nurul Hasan.

In 1997, the school celebrated its diamond jubilee with a grand function presided over by the governor of West Bengal, K. V. Raghunatha Reddy.

Don Bosco Liluah received the Calcutta Telegraph School of the Year award for "commitment to all-round excellence" in 2007, 2010, 2011and 2015.

Academic excellence continues at Don Bosco Liluah with Anurag Poddar placing 3rd in the all-India rankings for the 2013 ISC examinations by scoring 98.50%.

There are two playing fields, a series of gardens known as the Infant Jesus Park, and a combined basketball and tennis court (added as part of the 2012 Platinum Jubilee).

These events include debates, quizzes, science exhibitions, sports tournaments and singing and dance competitions.

Sports available at the school include basketball, cricket, football, volleyball, table tennis, and karate, with coaching facilities for the first three.

The school's annual magazine, The Canvas, is a collection of sketches, prose, poetry and accounts, created by the students.

[citation needed] Don Bosco Night School was started in 1976 by a group of past pupils and educates under-privileged young people in the area.

It was blessed by Archbishop Ferdinand Perier to serve the European and Anglo-Indian Catholics of the Liluah Railway Colony.