Donna Sue Campbell (née Burrows; born September 17, 1954) is an American politician and physician who is the 25th District member of the Texas Senate.

On July 31, 2012, she became the first person in Texas history to defeat an incumbent Republican senator, Jeff Wentworth of San Antonio, in a primary election.

from Texas Tech University Health Sciences Center in Lubbock in May 1989 and completed an internship in general surgery at Methodist Hospital in Dallas from 1989 to 1990.

[5][6] On her first day in the legislature, an aide to Senator John Whitmire passed out and Campbell provided assistance.

[10] On the last day of the regular legislative session in 2017, Democrat Jose Menendez of San Antonio used a filibuster to kill Campbell's bill which would have made it more difficult for municipalities to annex surrounding territory.

[13] In 2021, Campbell responded to the rise in mass shootings in Texas with a bill to furnish families with fingerprint and DNA kits, which could be used to identify their dead children.

[22] After the results were announced Campbell stated, "People were tired of the status quo government – that's the folks who came out and voted for us.

People identified with our message: smaller government, lower taxes and a vision for having a strong economy with job creation in the private sector.

[25] In the Republican primary on March 4, 2014, Campbell won re-nomination to her first four-year term in the state Senate.